225711

Nitric acid

70%, purified by redistillation, ≥99.999% trace metals basis

• Synonym(s): Aqua fortis, Azotic acid, Hydrogen nitrate
• Empirical Formula (Hill Notation): HNO₃
• CAS Number: 7697-37-2
• Molecular Weight: 63.01
• MDL number: MFCD00011349
• UNSPSC Code: 12352301
• eCl@ss: 38060304
• PubChem Substance ID: 24853516
• NACRES: NA.22

Properties

• vapor density: 1 (vs air)
• vapor pressure: 8 mmHg ( 20 °C)
• assay: ≥99.999% trace metals basis; 70%
• form: liquid
• purified by: redistillation
• color: colorless
• pH: <1.0
• bp: 120.5 °C (lit.)
• density: 1.413 g/mL at 20 °C (lit.)
• SMILES string: O[N+]([O-])=O
• InChI: 1S/HNO3/c2-1(3)4/h(H,2,3,4)
• InChI key: GRYLNZFGIOXLOG-UHFFFAOYSA-N

Description

General description

Nitric acid is generally used as a primary reagent for the nitration of organic molecules. It is also used as a strong oxidizing agent in organic synthesis to perform the oxidative transformations.

Application

Nitric acid used as a reagent in:

• The nitration of aromatic compounds, aromatic heterocycles, alkenes, active methylene carbons, etc.
• Selective oxidation of organosulfur compounds to corresponding sulfoxides using a solid acid catalyst.
• The oxidation of alcohols, aldehydes, esters, and heteroatoms.
• The aromatization and dehydrogenation reactions.

Safety Information

• pictograms: GHS03,GHS06,GHS05
• signalword: Danger
• hcodes: H272,H290,H314,H331
• pcodes: P210 - P220 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Eye Dam. 1 - Met. Corr. 1 - Ox. Liq. 3 - Skin Corr. 1A
• supp_hazards: EUH071
• Storage Class: 5.1B - Oxidizing hazardous materials
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable