T3146

Trimipramine maleate salt

≥98% (TLC), powder

• Empirical Formula (Hill Notation): C₂₀H₂₆N₂ · C₄H₄O₄
• CAS Number: 521-78-8
• Molecular Weight: 410.51
• EC Number: 208-318-3
• MDL number: MFCD00082376
• UNSPSC Code: 12352116
• PubChem Substance ID: 24278731
• NACRES: NA.77

Properties

• assay: ≥98% (TLC)
• form: powder
• color: white to off-white
• solubility: chloroform: soluble 50 mg/ml, clear, colorless to faintly yellow
• originator: Sanofi Aventis
• storage temp.: 2-8°C
• SMILES string: OC(=O)\C=C\C(O)=O.CC(CN(C)C)CN1c2ccccc2CCc3ccccc13
• InChI: 1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
• InChI key: YDGHCKHAXOUQOS-WLHGVMLRSA-N
• Gene Information: human ... HTR1A(3350) , HTR1B(3351) , HTR1D(3352) , HTR1E(3354) , HTR1F(3355) , HTR2A(3356) , HTR2B(3357) , HTR2C(3358) , HTR3A(3359) , HTR3B(9177) , HTR3C(170572) , HTR3D(200909) , HTR3E(285242) , HTR4(3360) , HTR5A(3361) , HTR5B(645694) , HTR6(3362) , HTR7(3363)

Description

Application

Trimipramine maleate has been used to develop chiral separation methods using capillary electrophoresis⁴.

Biochem/physiol Actions

Antidepressant; serotonin transport blocker that also blocks norepinephrine uptake.

Preparation Note

Trimipramine maleate is soluble in chloroform at 50 mg/ml to yield a clear, colorless to faint yellow solution.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H315,H319,H335,H361
• pcodes: P202 - P261 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges