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83697

Sigma-Aldrich

Rhodamine 6G

suitable for fluorescence, BioReagent

Synonym(s):

Basic Red 1

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About This Item

Linear Formula:
C28H31N2O3Cl
CAS Number:
989-38-8
Molecular Weight:
479.01
Colour Index Number:
45160
Beilstein/REAXYS Number:
3900071
EC Number:
213-584-9
MDL number:
MFCD00012665
UNSPSC Code:
12171500
PubChem Substance ID:
57652965
NACRES:
NA.32

product line

BioReagent

form

powder

solubility

H2O: soluble
ethanol: soluble

fluorescence

λex 528 nm; λem 551 nm in methanol

suitability

suitable for fluorescence

SMILES string

Cl.CCNc1cc2OC3=CC(=N/CC)\C(C)=CC3=C(c2cc1C)c4ccccc4C(=O)OCC

InChI

1S/C28H30N2O3.ClH/c1-6-29-23-15-25-21(13-17(23)4)27(19-11-9-10-12-20(19)28(31)32-8-3)22-14-18(5)24(30-7-2)16-26(22)33-25;/h9-16,29H,6-8H2,1-5H3;1H/b30-24+;

InChI key

VYXSBFYARXAAKO-WTKGSRSZSA-N

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Application

Rhodamine 6G has been used as a leukocyte marker to study the interaction between leukocytes and the vascular endothelium. It has also been used to label platelets.

Biochem/physiol Actions

Rhodamine 6G is a rhodamine analog useful in P-glycoprotein (Pgp) efflux assays. It has been used to characterize kinetics of multidrug resistance protein 1 (MRP1)-mediated efflux.
A rhodamine analog useful in Pgp efflux assays. Has been used to characterize kinetics of MRP1- mediated efflux.

Analysis Note

λmax. ∼530 nm, E(1%/1cm) ∼2000-2300 (96% Ethanol)

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Certificates of Analysis (COA)

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