695076

Formic acid

ACS reagent, ≥96%

• Linear Formula: HCOOH
• CAS Number: 64-18-6
• Molecular Weight: 46.03
• Beilstein/REAXYS Number: 1209246
• EC Number: 200-579-1
• MDL number: MFCD00003297
• UNSPSC Code: 12352106
• PubChem Substance ID: 329761713
• NACRES: NA.21

Properties

• grade: ACS reagent
• vapor density: 1.6 (vs air)
• vapor pressure: 44.8 mmHg ( 20 °C)
• assay: ≥96%
• form: liquid
• autoignition temp.: 1004 °F
• expl. lim.: 57 %
• refractive index: n20/D 1.370 (lit.)
• pH: 2.2 (20 °C, 2.2 g/L)
• bp: 100-101 °C (lit.)
• mp: 8.2-8.4 °C (lit.)
• solubility: water: miscible
• density: 1.22 g/mL at 25 °C (lit.)
• anion traces: chloride (Cl^-): ≤0.001%; sulfate (SO₄^2-): ≤0.003%; sulfite (SO₃^2-): passes test
• cation traces: Fe: ≤0.001%; NH₄⁺: ≤0.005%; heavy metals (as Pb): ≤0.001%
• application(s): sample preparation
• SMILES string: OC=O
• InChI: 1S/CH2O2/c2-1-3/h1H,(H,2,3)
• InChI key: BDAGIHXWWSANSR-UHFFFAOYSA-N

Description

General description

Formic acid is a simple carboxylic acid produced by the hydrolysis of methyl formate or formamide or from its salts. It is primarily used in dyeing, textile, leather, rubber, chemical, and pharmaceutical industries.

Application

Formic acid can be used as a reagent in the:

• Co-N_x-catalyzed one-pot reductive amination of carbonyl compounds with nitro compounds to synthesize secondary amines.
• Photoreduction of polycyclic and heterocyclic nitro arenes to corresponding amines.
• Pd-catalyzed chemoselective hydrogenation of olefins to saturated hydrocarbons.

Safety Information

• pictograms: GHS02,GHS06,GHS05
• signalword: Danger
• hcodes: H226,H302,H314,H331
• pcodes: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
• supp_hazards: EUH071
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 1
• flash_point_f: 121.1 °F - closed cup
• flash_point_c: 49.5 °C - closed cup