R7635
Ronidazole
analytical standard
Synonym(s):
1-Methyl-2-(carbamoyloxymethyl)-5-nitroimidazole
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About This Item
Empirical Formula (Hill Notation):
C6H8N4O4
CAS Number:
Molecular Weight:
200.15
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
analytical standard
Quality Level
assay
≥95%
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
−20°C
SMILES string
Cn1c(COC(N)=O)ncc1N(=O)=O
InChI
1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)
InChI key
PQFRTXSWDXZRRS-UHFFFAOYSA-N
General description
Ronidazole is a nitroimidazole compound, commonly used as antiprotozoal and antibacterial agent.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Ronidazole may be used as a reference standard in the determination of the analyte in poultry muscle and eggs using high-performance liquid chromatography with ultraviolet detection and confirmatory analysis by atmospheric pressure chemical ionization-mass spectrometry.
related product
Product No.
Description
Pricing
Storage Class
11 - Combustible Solids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Determination of dimetridazole, ronidazole and their common metabolite in poultry muscle and eggs by high performance liquid chromatography with UV detection and confirmatory analysis by atmospheric pressure chemical ionisation mass spectrometry.
Sams JM, et al.
Analyst, 123(1-2), 2545-2549 (1998)
Neurotoxicosis in 4 cats receiving ronidazole.
Terri W Rosado et al.
Journal of veterinary internal medicine, 21(2), 328-331 (2007-04-13)
J L Gookin et al.
Journal of veterinary internal medicine, 24(4), 1003-1007 (2010-05-25)
The mainstays of treatment for clinically important trichomonad infections are the 5-nitroimidazoles. Metronidazole resistance of feline Tritrichomonas foetus is presumed because of common treatment failure, and tinidazole does not consistently eradicate infection. To date, ronidazole is the only drug demonstrated
Malcolm Holliday et al.
Journal of feline medicine and surgery, 11(2), 131-134 (2008-09-09)
Faecal samples from 74 cats with chronic large bowel diarrhoea that were living in a rescue colony in Italy, were submitted for assessment of Tritrichomonas foetus by direct microscopy of faecal smears (n=20) and T foetus-specific culture (n=74), with confirmation
Synthesis and antiprotozoal activity of 1-(3-chloro-2-hydroxypropyl)-substituted nitroimidazoles.
Hoffer Max and Grunberg E
Journal of Medicinal Chemistry, 17(9), 1019-1020 (1974)
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