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B38503

Sigma-Aldrich

Bis(2-chloroethyl)amine hydrochloride

98%

Synonym(s):

β,β′-Dichlorodiethylamine hydrochloride, 1,5-Dichloro-3-azapentane hydrochloride, 2,2′-Dichlorodiethylamine hydrochloride, 2-Chloro-N-(2-chloroethyl)ethanamine hydrochloride, Bi(2-chloroethyl)amine hydrochloride, Bis(β-chloroethyl)amine hydrochloride, Bis(2-chloroethyl)ammonium chloride, Di(2-chloroethyl)amine hydrochloride, N,N-Bis(2-chloroethyl)amine hydrochloride, Nornitrogen mustard hydrochloride

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About This Item

Linear Formula:
(ClCH2CH2)2NH·HCl
CAS Number:
821-48-7
Molecular Weight:
178.49
Beilstein/REAXYS Number:
3550356
EC Number:
212-479-5
MDL number:
MFCD00012515
UNSPSC Code:
12352100
PubChem Substance ID:
24891737
NACRES:
NA.22

assay

98%

form

powder

mp

212-214 °C (lit.)

SMILES string

Cl.ClCCNCCCl

InChI

1S/C4H9Cl2N.ClH/c5-1-3-7-4-2-6;/h7H,1-4H2;1H

InChI key

YMDZDFSUDFLGMX-UHFFFAOYSA-N

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General description

Bis(2-chloroethyl)amine hydrochloride is used as a starting material to synthesize piperazine derivatives.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk_germany

WGK 3

flash_point_f

No information available.

flash_point_c

No information available.

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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The Journal of urology, 127(4), 818-822 (1982-04-01)
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Chemico-biological interactions, 39(1), 1-15 (1982-03-01)
Activated cyclophosphamide (CP) is known to achieve its cytotoxic and alkylating capacity upon spontaneous hydrolytic breakdown of the oxazaphosphorine ring structure. Treatment of yeast cells with the chemically activated form of CP (4-hydroperoxy-CP, 4-OOH-CP) and with several potentially toxic cleavage
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