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A47052

Sigma-Aldrich

6-Aminochrysene

95%

Synonym(s):

6-Chrysenamine

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About This Item

Empirical Formula (Hill Notation):
C18H13N
CAS Number:
2642-98-0
Molecular Weight:
243.30
EC Number:
220-149-7
MDL number:
MFCD00003699
UNSPSC Code:
12352100
PubChem Substance ID:
24890902
NACRES:
NA.22

assay

95%

form

solid

mp

209-211 °C (lit.)

SMILES string

Nc1cc2c3ccccc3ccc2c4ccccc14

InChI

1S/C18H13N/c19-18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H,19H2

InChI key

KIVUHCNVDWYUNP-UHFFFAOYSA-N

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Application

Produces tumors in mice.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Determination of polycyclic aromatic amines in skin by liquid chromatography with electrochemical detection.
L J Felice et al.
Journal of chromatography, 354, 442-448 (1986-02-28)
J M Salmon et al.
Cytometry, 9(1), 25-32 (1988-01-01)
The identification and quantification of fluorescent compounds in a complex fluorescence spectra are always difficult, especially in the case of low signal:noise ratio. We propose a computerised method that allows the resolution of low light level complex fluorescence spectra into
D Lautier et al.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 36(6), 685-691 (1988-06-01)
Previous reports on the inhibitory effect of 6-amino-chrysene (6AC) on benzo(a)pyrene (BP) metabolism using single living cells have suggested that aryl hydrocarbon hydroxylase (AHH) is not the only pathway for 6AC metabolism. We present here results demonstrating that direct glucuronidation
B G Lake et al.
Toxicology and applied pharmacology, 138(2), 231-241 (1996-06-01)
Precision-cut liver slices were prepared from male Sprague-Dawley rats (pretreated with or without Aroclor 1254), male Dunkin-Hartley guinea pigs, male cynomolgus monkeys, and humans. Liver slices were cultured for 24 hr using a dynamic organ culture system in medium containing
H Yamazaki et al.
Carcinogenesis, 15(3), 465-470 (1994-03-01)
In order to address the hypothesis that 6-aminochrysene (6-AC) is converted to genotoxic products by cytochrome P450 enzymes via two activation pathways (N-hydroxylation and epoxidation), the activation of 6-AC and trans-1,2-dihydro-1,2-dihydroxy-6-aminochrysene (6-AC-diol) to genotoxic metabolites was examined in rat and
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