725765

2-Methyl-4-isothiazolin-3-one

95%

• Synonym(s): 2-Methyl-3(2H)-isothiazolone
• Empirical Formula (Hill Notation): C₄H₅NOS
• CAS Number: 2682-20-4
• Molecular Weight: 115.15
• Beilstein/REAXYS Number: 606203
• EC Number: 220-239-6
• MDL number: MFCD01742315
• UNSPSC Code: 12352100
• PubChem Substance ID: 329764182
• NACRES: NA.21

Properties

• assay: ≥94.0% (GC); 95%
• form: lumps
• impurities: ≤5% water
• SMILES string: CN1SC=CC1=O
• InChI: 1S/C4H5NOS/c1-5-4(6)2-3-7-5/h2-3H,1H3
• InChI key: BEGLCMHJXHIJLR-UHFFFAOYSA-N

Description

Application

• Insights into the mechanisms of within-species variation in sensitivity to chemicals: A case study using daphnids exposed to CMIT/MIT biocide.: This study investigates the differential sensitivity of daphnids to 2-Methyl-4-isothiazolin-3-one, highlighting the biochemical mechanisms underlying these variations. The findings provide crucial insights for environmental safety assessments (Kim et al., 2023).
• Effects of the biocide methylisothiazolinone on Xenopus laevis wound healing and tail regeneration.: The study assesses the impact of 2-Methyl-4-isothiazolin-3-one on regenerative processes in amphibians, contributing to the understanding of its biological effects and potential toxicity (Delos Santos et al., 2016).
• T cell lymphomatoid contact dermatitis: a challenging case and review of the literature.: This review includes discussions on 2-Methyl-4-isothiazolin-3-one-induced contact dermatitis, providing valuable information for dermatological applications and safety assessments (Knackstedt and Zug, 2015).

Safety Information

• pictograms: GHS06,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H311,H314,H317,H330,H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1A
• supp_hazards: EUH071
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges