251933

4-Bromobutyryl chloride

95%

• Synonym(s): 4-Bromobutanoic acid chloride, 4-Bromobutanoyl chloride
• Linear Formula: BrCH₂CH₂CH₂COCl
• CAS Number: 927-58-2
• Molecular Weight: 185.45
• Beilstein/REAXYS Number: 1743026
• EC Number: 213-154-0
• MDL number: MFCD00000753
• UNSPSC Code: 12352200
• PubChem Substance ID: 24855170
• NACRES: NA.22

Properties

• assay: 95%
• reaction suitability: reagent type: cross-linking reagent
• refractive index: n20/D 1.492 (lit.)
• bp: 101 °C/37 mmHg (lit.)
• density: 1.602 g/mL at 25 °C (lit.)
• functional group: bromo
• SMILES string: BrCCCC(Cl)=O
• InChI: 1S/C4H6BrClO/c5-3-1-2-4(6)7/h1-3H2
• InChI key: LRTRXDSAJLSRTG-UHFFFAOYSA-N

Description

application

• Pharmaceutical research applications: 4-Bromobutyryl chloride was utilized in the synthesis of newly developed 3,4,5-trisubstituted-1,2,4-triazole derivatives. These derivatives demonstrated significant alpha-glucosidase inhibitory potential, suggesting their utility in managing diabetes through inhibition of carbohydrate hydrolyzing enzymes. This application underscores the importance of 4-Bromobutyryl chloride in the development of bioactive molecules for potential therapeutic use (Nafeesa et al., 2019).

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H314,H335
• pcodes: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH014
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 195.8 °F - closed cup
• flash_point_c: 91 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter