251259

Thionyl bromide

97%

• Synonym(s): Dibromo sulfoxide, Sulfur bromide oxide (SOBr₂)
• Linear Formula: SOBr₂
• CAS Number: 507-16-4
• Molecular Weight: 207.87
• EC Number: 208-064-3
• MDL number: MFCD00011448
• UNSPSC Code: 12352101
• PubChem Substance ID: 24855121
• NACRES: NA.22

Properties

• vapor pressure: 10 mmHg ( 31 °C)
• assay: 97%
• form: liquid
• refractive index: n20/D 1.675 (lit.)
• bp: 48 °C/20 mmHg (lit.)
• mp: −52 °C (lit.)
• density: 2.683 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: BrS(Br)=O
• InChI: 1S/Br2OS/c1-4(2)3
• InChI key: HFRXJVQOXRXOPP-UHFFFAOYSA-N

Description

Application

Thionyl bromide (SOBr₂) can be used as a brominating agent in organic synthesis for the bromination of alcohols, carboxylic acids, alkenes, and ketones.
SoBr₂ can be used in the synthesis of:      

• ortho

• -Bromoanilides by bromination of ortho C-H bonds of the aryhydroxylamines.      
• β-Amino bromides from β-aminoalcohols in the presence of DMF as a solvent.      
• 4,8-Dibromobenzo[1,2-c;4,5-c′]bis[1,2,5]thiadiazole from 1,2,4,5-tetraaminobenzene tetrahydrobromide.

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H312 + H332,H314
• pcodes: P261 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Skin Corr. 1B
• supp_hazards: EUH014
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter