COQ6
coenzyme Q6 monooxygenase
Synonyms:
CGI10, COQ10D6
Species:
Human COQ6 (51004), Mouse Coq6 (217707), Rat Coq6 (299195), sheep COQ6 (101105664), Domestic Rabbit COQ6 (100342074), domestic guinea pig Coq6 (100731940), naked mole-rat Coq6 (101706068), cow COQ6 (511624), chicken COQ6 (423342), dog COQ6 (490778) ...More
UniProtKB ID:
Gene ID:
- Human(51004) Summary: The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2012]
- Mouse(217707) coenzyme Q6 homolog (yeast)
- Rat(299195) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- sheep(101105664) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- Domestic Rabbit(100342074) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- domestic guinea pig(100731940) coenzyme Q6 monooxygenase
- naked mole-rat(101706068) coenzyme Q6 monooxygenase
- cow(511624) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- chicken(423342) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- dog(490778) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- domestic cat(101090023) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- Horse(100056420) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
- Zebrafish(751691) coenzyme Q6 homolog, monooxygenase (S. cerevisiae)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-COQ6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry