PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
Synonyms:
LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1
Species:
Human PPARGC1A (10891), Mouse Ppargc1a (19017), Rat Ppargc1a (83516), chicken PPARGC1A (422815), domestic guinea pig Ppargc1a (100721512), naked mole-rat Ppargc1a (101703716), Goat PPARGC1A (100861288), sheep PPARGC1A (443270), Domestic Rabbit PPARGC1A (100349219), cow PPARGC1A (338446) ...More
UniProtKB ID:
Gene ID:
- Human(10891) Summary: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
- Mouse(19017) peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
- Rat(83516) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- chicken(422815) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- domestic guinea pig(100721512) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- naked mole-rat(101703716) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- Goat(100861288) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- sheep(443270) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- Domestic Rabbit(100349219) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- cow(338446) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- Horse(100055716) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- domestic cat(101081802) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- dog(479127) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
- Zebrafish(553418) peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PGC-1α antibody produced in mouse, clone 1F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-PGC-1α(N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-PGC1A antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
canine, human, mouse, rat
Application
ELISA
western blot
western blot
Anti-PPARGC1A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, rabbit, rat
Application
western blot
esiRNA
Product Number
Description
Species