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MilliporeSigma

CHRM5

cholinergic receptor, muscarinic 5

Synonyms:
HM5
Species:
UniProtKB ID:
Gene ID:
  • Human(1133) Summary: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008]
  • Mouse(213788) cholinergic receptor, muscarinic 5
  • Rat(53949) cholinergic receptor, muscarinic 5
  • naked mole-rat(101719201) cholinergic receptor, muscarinic 5
  • Domestic Rabbit(100342984) cholinergic receptor, muscarinic 5
  • dog(487472) cholinergic receptor, muscarinic 5
  • Horse(100057856) cholinergic receptor, muscarinic 5
  • cow(281686) cholinergic receptor, muscarinic 5
  • sheep(101110766) cholinergic receptor, muscarinic 5
  • domestic cat(101097246) cholinergic receptor, muscarinic 5
  • chicken(428881) cholinergic receptor, muscarinic 5
  • domestic guinea pig(100379240) cholinergic receptor, muscarinic 5

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Small Molecule - Agonist

Product Number
Description
Species
Acetyl-β-methylcholine chloride, ≥98% (TLC), powder,
Species
human
Oxotremorine M, solid,
Species
human
Pilocarpine nitrate salt, ≥98% (HPLC),
Species
human
Pilocarpine hydrochloride, ≥99% (titration), powder,
Species
human
(±)-Muscarine chloride hydrate, ≥98% (HPLC),
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Ipratropium bromide monohydrate, ≥98% (TLC), powder,
Species
human
Oxybutynin chloride, ≥98% (TLC), powder,
Species
human
(−)-Scopolamine hydrobromide trihydrate, ≥98% (HPLC), powder,
Species
human
(−)-Scopolamine N-butyl bromide, ≥98% (TLC), powder,
Species
human
Propantheline bromide, ≥97% (TLC), powder,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHRM5 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-CHRM5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-CHRM5, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry

Small Molecule - Inhibitor

Product Number
Description
Species
Amitriptyline hydrochloride, ≥98% (TLC), powder,
Species
human
Doxepin hydrochloride, ~85% E-isomer basis, ≥98% (GC), 15% Z-isomer basis, powder,
Species
human
Harmaline, ≥95%,
Species
human, rat

Small Molecule - Ligand

Product Number
Description
Species
Aminobenztropine, solid,
Species
human

Proteins

Product Number
Description
Species
ChemiScreen Membrane Preparation
Recombinant Human M5 Muscarinic Acetylcholine Receptor
, Human M5 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CHRM5,
Species
human