sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

GF18587975

Nickel, sphere, 100pcs, diameter 1.0mm, precision sphere grade 200, 99%

GF79898922

Nickel, foil, 10mm disks, thickness 0.25mm, annealed, 99.98%

GF69262285

Nickel, foil, 15mm disks, thickness 0.0125mm, 99.99+%

GF46466860

Nickel, foil, 10mm disks, thickness 0.01mm, 99.95%

GF22812634

Nickel, insulated wire, 10m, conductor diameter 0.025mm, insulation thickness 0.0035mm, polyimide insulation

GF77617435

Nickel, foil, 50x50mm, thickness 0.50mm, annealed, 99%

GF43591934

Nickel, foil, 10mm disks, thickness 0.02mm, 99.9%

GF14281815

Nickel, foil, 25x25mm, thickness 2.0mm, as rolled, 99.99+%

GF92400735

Nickel, tube, 500mm, outside diameter 2.0mm, inside diameter 1.6mm, wall thickness 0.2mm, hard, 99.5%

GF85934212

Nickel, foil, 25x25mm, thickness 0.15mm, annealed, 99%

GF50050213

Nickel, wire reel, 10m, diameter 0.75mm, as drawn, 99%

GF17268880

Nickel, foil, 150x150mm, thickness 0.3mm, annealed, 99%

GF82903787

Nickel, foil, 4mm disks, thickness 0.01mm, 99.95%

GF21073407

Nickel, wire reel, 100m, diameter 0.75mm, as drawn, 99%

GF00552967

Nickel, foil, 0.5m coil, thickness 0.01mm, 99.95%

GF28484556

Nickel, foil, 50x50mm, thickness 0.1mm, annealed, 99%

GF83020935

Nickel, foil, 25x25mm, thickness 0.50mm, annealed, 99%

GF10085240

Nickel, pellets, 20g, max. size 10mm, 99.99+%

GF21346848

Nickel, rod, 100mm, diameter 1.5mm, 99.99+%

GF35122092

Nickel, mesh, 65x65mm, nominal aperture 0.04mm, thickness 0.004mm, wire diameter 0.011mm, 500 wires/inch, open area 60%, electro-formed mesh, 99.9%