Single-Use Mixers
Ranging from 10 to 3000 L, our single-use mixers have been designed to meet the broadest range of requirements. Mobius® single-use mixers efficiently blend pharmaceutical ingredients and prepare process solutions like buffers and media. Unlike traditional stainless steel mixers which require downtime for cleaning processes, Mobius® single-use mixers minimize it with uncompromised mix quality. For antibody drug conjugate manufacturing, the Mobius® ADC Reactor is specifically designed for the key conjugation step.
See related resources below or contact us.
Mobius® MIX: the mixing solution of choice for gentle mixing applications such as protein and shear-sensitive product homogenization
- Available in 10 L, 50 L, 100 L, 200 L, 500 L, and 1,000 L sizes (jacketed stainless steel or plastic depending on size)
- Fast, easy setup and use
- Compact footprint and mobile carrier construction for enhanced flexibility
- Instant-on electronics with no warmup needed
Mobius® Power MIX: the mixing solution of choice for hard-to-dissolve materials and buffer preparation
- Available in 100 L, 200 L, 500 L, 1,000 L, 2,000 L, 2,500 L, and 3,000 L (jacketed stainless steel or plastic depending on size)
- Stainless steel versions have wide doors that open to one half the mixer's diameter for easy bag loading
- Optional integrated load cells and temperature sensor on stainless steel versions
Mobius® ADC Reactor: A SCALABLE FAMILY OF SINGLE-USE MIXING SYSTEMS PERFECTED FOR BIOCONJUGATION
- Available in 10 L, 100 L, and 500 L sizes
- Single-use components with proven compatibility with solvents such as DMAc and DMSO, ensuring product quality
- Designed with the requirements of conjugation in mind, with additional ports for tailored material handling
Learn more about the Mobius® ADC Reactor.
Control Boxes
Mobius® mixers and Mobius® ADC Reactors can be monitored and controlled locally or remotely with the Ready to Connect control box.
For Mobius® MIX and Power MIX, the smart control box with Bio4C ACE™ Control Software enables remote monitoring of critical process parameters, supplies advanced process control, and facilitates regulatory compliance during mixing operations.
Single-use mixer bags are made either with PureFlex™ or with Ultimus® film. The PureFlex™ family of single-use process container films are high purity, medical grade and coextruded to provide strength, flexibility, excellent gas barrier performance, and inert contact. Additionally, Ultimus® Film was designed for your more challenging single-use bioprocessing liquid applications, increasing durability while maintaining the ease of handling, flexibility, and conformity that single-use bioprocessing demands.
Related Resources
- Data Sheet: Mobius® Power MIX Single-use Mixing Systems
The Mobius® Power MIX single-use mixing systems combine high performance mixing technology with design features that make them easy-to-use. The impeller design and motor are based on our magnetically coupled NovAseptic® mixing technology, a proven mixing technology in stainless steel tanks.
- Data Sheet: Mobius® MIX Single-use Mixing Systems
The Mobius® MIX single-use mixing solution delivers advanced technology for mixing pharmaceutical ingredients from intermediate to final drug products and for the preparation of process solutions, such as buffers and media.
- Data Sheet: Mobius® ADC Reactor
A scalable family of single-use mixers perfected for bioconjugation.
- Article: Mobius® ADC Reactor Components Chemical Compatibility
It is important to evaluate the compatibility of the single-use components of an equipment dedicated to conjugation such as the Mobius® ADC reactor.
- Technical Brief: Mobius® ADC Reactor for Conjugation
The Mobius® ADC Reactor is designed to meet the precise demands of bioconjugation.
- Infographic: Single-use benefits for ADC manufacturing
The Mobius® ADC Reactor allows for flexible manufacturing that reduces risk and waste for maximum efficiency.
- White Paper: Performance Characteristics of the Mobius® ADC Reactor for Conjugation
This white paper describes a series of studies using a model fluid to evaluate the mixing performance of Mobius® ADC Reactor for conjugation.
- Application Note: Comparison Between Experimental Data and Computational Fluid Dynamics in Mixing Applications
In biomanufacturing processes, mixing is ubiquitous. Examples include buffer and media preparation, stirred tank bioreactor/fermentor operation, virus inactivation, DNA digestion, final formulation and beyond.
- Technical Brief: Mobius® MIX500 Disposable Mixing System Characterization
The need for faster cycle times and higher levels of operational flexibility has accelerated the adoption of single-use processing solutions in the biopharmaceutical industry.
- Application Note: Mobius® Power MIX: Scalability in Mixing
The Mobius® Power MIX single-use systems provide an effective mixing platform for biopharmaceutical manufacturing in a range of sizes including 100, 200, 500, 1000 and 2000 L.
- Application Note: Compatibility of a Mobius® Single-use Solution for ADC Processing
Antibody Drug Conjugates (ADCs) are a class of biomolecules that has seen rapid growth as an oncology therapeutic.
- Application Note: Mobius® Single-use Mixing Solution Characterizing Liquid Blend Times Versus Viscosity
This technical study characterizes the liquid blend time for each Mobius® single-use mixing system at a range of volumes, RPM, and viscosities, using a pH shift technique.
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