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426008

Sigma-Aldrich

Carbofuran

98%

Synonym(s):

2,3-Dihydro-2,2-dimethyl-7-benzofuranol N-methylcarbamate

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About This Item

Empirical Formula (Hill Notation):
C12H15NO3
CAS Number:
1563-66-2
Molecular Weight:
221.25
Beilstein:
1428746
EC Number:
216-353-0
MDL number:
MFCD00041819
UNSPSC Code:
12352100
PubChem Substance ID:
24866678
NACRES:
NA.22

Assay

98%

form

crystals

mp

150-153 °C (lit.)

SMILES string

CNC(=O)Oc1cccc2CC(C)(C)Oc12

InChI

1S/C12H15NO3/c1-12(2)7-8-5-4-6-9(10(8)16-12)15-11(14)13-3/h4-6H,7H2,1-3H3,(H,13,14)

InChI key

DUEPRVBVGDRKAG-UHFFFAOYSA-N

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General description

Carbofuran is an anticholinesterase carbamate, which is commonly used as a pesticide. Its literature data on toxicity have been reviewed. The effect from exposure to carbofuran has been investigated on acetylcholinesterase (AChE) activity in the brain and muscle of common carp (Cyprinus carpio). Degradation studies using ozone, UV radiation and advanced oxidation processes (AOPs) and by photocatalytic degradation have been investigated. Ultra high performance liquid chromatography (UHPLC) method to determine the carbofuran in water samples have been developed with satisfactory results.

Pictograms

Skull and crossbonesEnvironment
GHS06,GHS09

Signal Word

Danger

Hazard Statements

H300 + H330,H311,H410

Hazard Classifications

Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Aquatic Acute 1 - Aquatic Chronic 1

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Degradation of carbofuran by using ozone, UV radiation and advanced oxidation processes.
Benitez FJ, et al.
Journal of Hazardous Materials, 89(1), 51-65 (2002)
Photocatalytic degradation of carbofuran using semiconductor oxides.
Mahalakshmi M, et al.
Journal of Hazardous Materials, 143(1), 240-245 (2007)
Jorge Morales et al.
Chemosphere, 89(11), 1267-1271 (2012-06-22)
The influence of humic aggregates in water solution upon the chemical stability of carbofuran (CF) and the carbofuran-derivatives, 3-hydroxy-carbofuran (HCF) and 3-keto-carbofuran (KCF), has been investigated in basic media. An inhibition upon the basic hydrolysis of 3-hydroxy-carbofuran and 3-keto-carbofuran (≈
Ratnesh Kumar Sharma et al.
Disease markers, 32(3), 153-163 (2012-03-02)
Various efforts have been made in past in order to predict the underlying mechanism of pesticide-induced toxicity using in vitro and animal models, however, these predictions may or may not be directly correlated with humans. The present study was designed
Ahmed S A Harabawy et al.
Ecotoxicology and environmental safety, 103, 61-67 (2014-01-28)
The present work aimed to evaluate the toxic effects of two sublethal concentrations of carbofuran pesticide (0.16 and 0.49mg/L, for 35 days) on hematological and blood biochemical parameters of catfish, Clarias gariepinus, and to evaluate the genotoxic potential of carbofuran
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