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Key Documents

389137

Sigma-Aldrich

(2-Hydroxyethyl)-β-cyclodextrin

extent of labeling: ~0.7 mol per mol cellulose

Synonym(s):

2-HE-β-CD, 2-hydroxyethyl-β-CD, HP-β-CD

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About This Item

CAS Number:
UNSPSC Code:
12352201
NACRES:
NA.22

form

powder

optical activity

[α]20/D 120 to 140°, c = 1 in H2O

extent of labeling

~0.7 mol per mol cellulose

mp

260 °C (dec.) (lit.)

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General description

(2-Hydroxyethyl)-β-cyclodextrin is a chemically modified, hydroxyalkylated derivative of cyclodextrin that finds potential use mainly in cosmetics application.

Application

(2-Hydroxyethyl)-β-cyclodextrin may be used as a chiral selector to resolve cathinone derivatives, lactic acid and oxybutynin enantiomers by capillary electrophoresis (CE), and high performance liquid chromatography (HPLC) techniques.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Equilibrium studies on enantioselective extraction of oxybutynin enantiomers by hydrophilic beta-cyclodextrin derivatives
Tang K, et al.
AIChE Journal, 57(11), 3027-3036 (2011)
L Saavedra et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 766(2), 235-242 (2002-02-05)
The optimization of the separation conditions of the two optical isomers of lactic acid by a factorial design is reported. Initially, different chiral selectors were systematically investigated and then a experimental design with three quantitative factors (cyclodextrin concentration and background
Paweł Mateusz Nowak et al.
Electrophoresis, 39(19), 2406-2409 (2018-07-13)
Methcathinone (ephedrone), 4-methylmethcathinone (mephedrone), and 3-methylmethcathinone (metaphedrone) are toxicologically-important cathinone derivatives used commonly as designer drugs. In this work we show the first method allowing to separate simultaneously all these molecules in a chiral medium, ensuring good resolution between all
Design of Nanostructures for Versatile Therapeutic Applications
Pharmaceutical Nanotechnology (2018)
Cyclodextrin Fundamentals, Reactivity and Analysis
Environmental Chemistry for a Sustainable World (2018)

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