O5632

Linoleic acid, conjugated methyl ester

• Synonym(s): CLA methyl ester, Octadecadienoic acid, conjugated, methyl ester
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• biological source: plant (safflower)
• Assay: ≥99% (GC)
• form: liquid
• technique(s): GC/MS: suitable; HPLC: suitable
• impurities: ≤1% Linoleic acid methyl ester
• functional group: carboxylic acid; ester
• lipid type: omega FAs
• shipped in: ambient
• storage temp.: −20°C

Description

General description

Conjugated linoleic acid (CLA) describes the positional and geometric isomers of C_18:2 fatty acids (FA) with a conjugated double bond. cis-9, trans-11 CLA are considered as the major isomers of CLA, based on in vitro experiments and animal studies in milk. The major source of CLA in human diet is the ruminant fat.

Application

Linoleic acid, conjugated methyl ester (CLA) has been used as a standard for the determination of isomers of CLA in milk samples by high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry. It has also been used in the production of sn-1,3 diacyl glycerol.

Biochem/physiol Actions

Conjugated linoleic acid (CLA) isomers as supplements inhibit the growth of numerous human cancer cell lines. It also possesses immunostimulant properties, prevents diabetes and reduces atherosclerosis.

Other Notes

A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acid methyl esters. Isomer ratio may vary from lot to lot.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves