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H3647

Sigma-Aldrich

Methyl 4-hydroxybenzoate

BioReagent, suitable for insect cell culture

Synonym(s):

p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN

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About This Item

Linear Formula:
HOC6H4CO2CH3
CAS Number:
99-76-3
Molecular Weight:
152.15
Beilstein:
509801
EC Number:
202-785-7
MDL number:
MFCD00002352
UNSPSC Code:
12352207
PubChem Substance ID:
24895585
NACRES:
NA.75

biological source

synthetic

product line

BioReagent

Assay

≥99.0% (HPLC)

form

powder or crystals

technique(s)

cell culture | insect: suitable

mp

125-128 °C (lit.)

solubility

ethanol: 50 mg/mL, clear, colorless

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

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General description

Parabens are ester derivatives of hydroxybenzoic acid. Methyl 4-hydroxybenzoate is a short-chain paraben, suitable for applications in food. It is found in cloudberry, white wine, yellow passion fruit, and bourbon vanilla.

Application

Methyl 4-hydroxybenzoate has been used:
  • to wash mites from the cells of Apis mellifera workers preceding the harvest of mite saliva
  • as a component of grape/apple juice agar plates to culture Drosophila for the extraction of ovaries/embryos
  • in studies on sterol hormones such as testosterone biosynthesis

Pictograms

Environment
GHS09

Hazard Statements

H411

Precautionary Statements

P273 - P391 - P501

Hazard Classifications

Aquatic Chronic 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

334.4 °F

Flash Point(C)

168 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Ivo A Telley et al.
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Spindle assembly and chromosome segregation rely on a complex interplay of biochemical and mechanical processes. Analysis of this interplay requires precise manipulation of endogenous cellular components and high-resolution visualization. Here we provide a protocol for generating an extract from individual
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The Varroa destructor (Acari Varroidae) mite is a serious threat to honey bee due to hemolymph feeding and virus transmission. Mite salivary proteins are involved in these interactions. However, the salivary secretome has not been previously characterized. In this paper
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