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Key Documents

L-911

Supelco

Lorazepam-d4 solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C15D4H6Cl2N2O2
CAS Number:
Molecular Weight:
325.18
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

SMILES string

ClC1=CC=C2C(C(C3=C([2H])C([2H])=C([2H])C([2H])=C3Cl)=NC(O)C(N2)=O)=C1

InChI

1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)/i1D,2D,3D,4D

InChI key

DIWRORZWFLOCLC-RHQRLBAQSA-N

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General description

A stable-labeled internal standard suitable for quantitation of lorazepam levels in urine, serum, or plasma by LC/MS or GC/MS for urine drug testing, clinical toxicology, or forensic analysis. Lorazepam, also known by trade names Ativan® or Orfidal, is a benzodiazepine often prescribed for treatment of anxiety disorders.

Application



  • Application in toxicological analysis: Lorazepam-d₄ was utilized as an analytical reference standard in a study aimed at the detection and quantification of lorazepam in human hair by GC-MS/NCI, assisting in forensic investigations related to traffic accidents (Cirimele et al., 1996).


  • Confirmation of urinary benzodiazepine metabolites: A research paper detailed the use of Lorazepam-d₄ in GC-MS methodologies to confirm the presence of benzodiazepine metabolites in urine, providing crucial data for both clinical and forensic settings (Meatherall, 1994).


Legal Information

Ativan is a registered trademark of American Home Product Corp.
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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