C-216

Cortisol-¹³C₃ solution

100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₈¹³C₃H₃₀O₅
• CAS Number: 1996649-39-8
• Molecular Weight: 365.44
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL in methanol
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: −20°C

Description

Application

• Automated analysis of cortisol metabolites using Cortisol-¹³C₃: An innovative method utilizing online in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry was developed for the automated analysis of sulfated steroid metabolites in saliva samples, including those labeled with Cortisol-¹³C₃. This technique provides a robust tool for biochemical research focused on hormone analysis and metabolic studies (Kataoka and Nakayama, 2022).


• Validation of LC-MS/MS methods for cortisol analysis using Cortisol-¹³C₃: A comprehensive validation study for an LC-MS/MS method to determine both free and total forms of urinary cortisol and its metabolites was conducted, demonstrating the utility of stable isotope-labeled standards like Cortisol-¹³C₃. This method is critical for precise quantitative analysis in clinical diagnostics and pharmaceutical research (Cuzzola, Mazzini, and Petri, 2014).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225,H301 + H311 + H331,H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Target Organs: Eyes
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 51.8 °F - closed cup
• Flash Point(C): 11.0 °C - closed cup