162973

2-[2-(2-Chloroethoxy)ethoxy]ethanol

96%

• Synonym(s): Triethylene glycol monochlorohydrin
• Linear Formula: Cl(CH₂CH₂O)₂CH₂CH₂OH
• CAS Number: 5197-62-6
• Molecular Weight: 168.62
• Beilstein: 1739194
• EC Number: 225-984-0
• MDL number: MFCD00002874
• UNSPSC Code: 12352100
• PubChem Substance ID: 24850015
• NACRES: NA.22

Properties

• Assay: 96%
• form: liquid
• refractive index: n20/D 1.458 (lit.)
• bp: 117-120 °C/5 mmHg (lit.)
• density: 1.16 g/mL at 25 °C (lit.)
• SMILES string: OCCOCCOCCCl
• InChI: 1S/C6H13ClO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-6H2
• InChI key: KECMLGZOQMJIBM-UHFFFAOYSA-N

Description

Application

2-[2-(2-Chloroethoxy)ethoxy]ethanol was used in the synthesis of 1-[3-(2-aminoethyl)-1H-indol-5-yloxy]-3,6-dioxa-8-mercaptooctane. It was also used in the synthesis of modified oligonucleotides bearing a disulfide or a thiol function at the 3′-end and other modifications at the 5′-end.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 3
• Flash Point(F): 224.6 °F - closed cup
• Flash Point(C): 107 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves