跳轉至內容
Merck

Antifungal agents. Part I. Amphotericin B preparations and flucytosine.

Mayo Clinic proceedings (1998-12-30)
R Patel
摘要

Traditionally, amphotericin B has been the cornerstone of antifungal treatment. Toxicity, however, is a major dose-limiting factor of amphotericin B deoxycholate. Nevertheless, it continues to have a major role in the treatment of deep-seated mycotic infections. Recently, less nephrotic lipid formulations, including amphotericin B lipid complex, amphotericin B cholesteryl sulfate, and liposomal amphotericin B, have been introduced. The pharmacologic properties, main indications, recommended dosages, related costs, and adverse effects of these various preparations are summarized in this review. Orally administered flucytosine is useful in certain infections, particularly cryptococcal meningitis, but it should be used with caution in patients with renal insufficiency.

材料
產品編號
品牌
產品描述

Sigma-Aldrich
5-氟胞嘧啶, nucleoside analog
氟胞嘧啶, European Pharmacopoeia (EP) Reference Standard
Sigma-Aldrich
5-氟胞嘧啶, Vetec, reagent grade, 99%