Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions.

Dirhodium tetracarboxylate derived from adamantylglycine as a chiral catalyst for carbenoid reactions.

Organic letters (2006-07-28)

Ravisekhara P Reddy, Gene H Lee, Huw M L Davies

摘要

[reaction: see text] The dirhodium tetracarboxylate, Rh2(S-PTAD)4, derived from adamantylglycine, is a very effective chiral catalyst for carbenoid reactions. High asymmetric induction was obtained in Rh2(S-PTAD)4-catalyzed intramolecular C-H insertion (94% ee), intermolecular cyclopropanation (99% ee), and intermolecular C-H insertion (92% ee).