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Merck
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文件

SML3078

Sigma-Aldrich

JT003 trifluoroacetate

≥95% (HPLC)

同義詞:

P-Nva-LYYFA trifluoroacetate

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About This Item

經驗公式（希爾表示法）:
C46H62N8O9 · xC2HF3O2
分子量：:
871.03 (free base basis)
分類程式碼代碼:
51111800
NACRES:
NA.77

品質等級

100

化驗

≥95% (HPLC)

形狀

film or powder

顏色

white to off-white

儲存溫度

−20°C

生化／生理作用

JT003 is potent dual agonist of adiponectin receptors AdipoR1/AdipoR2 that potently improves insulin resistance in high fat diet induced nonalcoholic steatohepatitis (NASH) mice. JT003 inhibits hepatic stellate cells (HSCs) activation in CCl4 induced liver fibrosis.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Michishige Terasaki et al.
International journal of molecular sciences, 21(13) (2020-07-11)
Dipeptidyl peptidase-4 (DPP-4) inhibitors have been reported to play a protective role against atherosclerosis in both animal models and patients with type 2 diabetes (T2D). However, since T2D is associated with dyslipidemia, hypertension and insulin resistance, part of which are
Hongjiao Xu et al.
Nature communications, 11(1), 5807-5807 (2020-11-18)
Chronic nonalcoholic steatohepatitis (NASH) is a metabolic disorder that often leads to liver fibrosis, a condition with limited therapy options. Adiponectin is an adipocytokine that regulates glucose and lipid metabolism via binding to its receptors AdipoR1 and AdipoR2, and AdipoRs

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