SAB5701760

Anti-Phospho-Lck-Y505 antibody produced in rabbit

• 分類程式碼代碼: 12352203
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: liquid
• 物種活性: mouse, rat, human
• 濃度: 3.79 mg/mL
• 技術: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:1000
• UniProt登錄號: P06239
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: phosphorylation (pTyr505)
• 基因資訊: human ... LCK(3932)

描述

一般說明

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.

免疫原

A synthetic phosphorylated peptide around Y505 of human Lck (NP_001036236.1).

外觀

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable