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SAB4300398

Sigma-Aldrich

Anti-MAP3K5 (Ab-83) antibody produced in rabbit

affinity isolated antibody

同義詞:

Anti-ASK1 antibody produced in rabbit, Anti-MAPKKK5 antibody produced in rabbit, Anti-MEKK5 antibody produced in rabbit, Anti-mitogen-activated protein kinase kinase kinase 5 antibody produced in rabbit

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

~155 kDa

物種活性

human

濃度

1 mg/mL

技術

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
indirect immunofluorescence: 1:100-1:200
western blot: 1:500-1:1000

同型

IgG

免疫原序列

(G-S-S-V-G)

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... MAP3K5(4217)

免疫原

Peptide sequence around aa. 81-85 (G-S-S-V-G), according to the protein MAP3K5.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

Component of a protein kinase signal transduction cascade. Phosphorylates and activates MAP2K4 and MAP2K6, which in turn activate the JNK and p38 MAP kinases, respectively. Overexpression induces apoptotic cell death.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Philipp Grubwieser et al.
Frontiers in microbiology, 14, 1223113-1223113 (2023-08-28)
Klebsiella pneumoniae (KP) is a major cause of hospital-acquired infections, such as pneumonia. Moreover, it is classified as a pathogen of concern due to sprawling anti-microbial resistance. During infection, the gram-negative pathogen is capable of establishing an intracellular niche in
Alexander Hoffmann et al.
EBioMedicine, 71, 103568-103568 (2021-09-07)
Iron deficiency anaemia (IDA) is a major health concern. However, preventive iron supplementation in regions with high burden of infectious diseases resulted in an increase of infection related morbidity and mortality. We fed male C57BL/6N mice with either an iron
Philipp Grubwieser et al.
Frontiers in cellular and infection microbiology, 12, 875543-875543 (2022-06-07)
Pneumonia is often elicited by bacteria and can be associated with a severe clinical course, respiratory failure and the need for mechanical ventilation. In the alveolus, type-2-alveolar-epithelial-cells (AECII) contribute to innate immune functions. We hypothesized that AECII actively adapt cellular
Alina Chakraborty et al.
Genome research, 32(7), 1271-1284 (2022-07-21)
Intronic polyadenylation (IPA) isoforms, which contain alternative last exons, are widely regulated in various biological processes and by many factors. However, little is known about their cytoplasmic regulation and translational status. In this study, we provide the first evidence that

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