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Merck
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文件

S3066

Sigma-Aldrich

SKF-89626 hydrobromide

>98% (HPLC), solid

同義詞:

4-(3,4-Dihydroxyphenyl)-4,5,6,7-tetrahydro­thieno[2,3-c]pyridine

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About This Item

經驗公式（希爾表示法）:
C13H13NO2S · HBr
分子量：:
328.22
MDL號碼:
MFCD04040024
分類程式碼代碼:
12352200
PubChem物質ID:
24278702

化驗

>98% (HPLC)

形狀

solid

顏色

white

溶解度

H2O: soluble 11 mg/mL

SMILES 字串

Br[H].Oc1ccc(cc1O)C2CNCc3sccc23

InChI

1S/C13H13NO2S.BrH/c15-11-2-1-8(5-12(11)16)10-6-14-7-13-9(10)3-4-17-13;/h1-5,10,14-16H,6-7H2;1H

InChI 密鑰

QAIGGSDECIJPNW-UHFFFAOYSA-N

基因資訊

human ... DRD1(1812)

應用

SKF-89626 hydrobromide may be used in dopaminergic cell signaling studies.

生化／生理作用

SKF-89626 is an isoquinoline derivative that fully antagonizes dopamine D1 receptor and stimulates adenylate cyclase and modulates dopaminergic-mediated cell responses.
D1 dopamine receptor agonist.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

分析證明 (COA)

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E B Nielsen et al.
European journal of pharmacology, 160(2), 253-262 (1989-01-31)
Dopamine (DA) D-1 and D-2 receptor agonists and antagonists were characterized in receptor binding and adenylate cyclase assays with respect to affinity, selectivity and efficacy. The ability of the ligands to interact with the discriminative stimulus effects of d-amphetamine (AMPH)
P H Andersen et al.
European journal of pharmacology, 188(6), 335-347 (1990-06-12)
Dopamine receptor selectivity was investigated for a number of dopamine receptor agonists. In vitro, the benzazepine derivatives, e.g., SKF 38393 and SKF 75670 as well as the isoquinoline derivatives, SKF 89626 and SKF 89615, were D1 receptor-selective. All other compounds

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