推薦產品
化驗
≥98% (TLC)
品質等級
形狀
powder
溶解度
acetic acid: 49.00-51.00 mg/mL, clear, colorless
儲存溫度
−20°C
SMILES 字串
CNc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
InChI
1S/C11H15N5O3/c1-12-10-9-11(14-4-13-10)16(5-15-9)8-2-6(18)7(3-17)19-8/h4-8,17-18H,2-3H2,1H3,(H,12,13,14)/t6-,7+,8+/m0/s1
InChI 密鑰
DYSDOYRQWBDGQQ-XLPZGREQSA-N
應用
N6-甲基-2′-脱氧腺苷已用作标准品,结合超高效液相色谱法和三重四极杆质谱法(UHPLC-QQQ-MS/MS)来测定基因组DNA中的修饰碱基水平。它还用于研究其促进红系祖细胞增殖潜力。
生化/生理作用
N6-甲基-2′-脱氧腺苷(N6-Me-dAdo)是N6-甲基2′-脱氧腺苷3′,5′-二磷酸盐(N6MABP)的前体,后者是P2Y受体的一种竞争性和选择性抑制剂。它位于转录起始位点,在莱茵衣藻的增强基因表达中起作用。N6-Me-dAdo可增强内部转座因子,在果蝇的发育过程中处于较高水平。它在原核生物和原生生物中参与基因转录、DNA修复和复制的调节。与基因体互补的N6-Me-dAdo可能诱导人细胞的基因表达。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。
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Reaction of the rodent carcinogen acrylonitrile (AN) at pH 5.0 and/or pH 7.0 for 10 and/or 40 days with 2'-deoxyadenosine (dAdo), 2'-deoxycytidine (dCyd), 2'-deoxyguanosine (dGuo), 2'-deoxyinosine (dIno), N6-methyl-2'-deoxyadenosine (N6-Me-dAdo) and thymidine (dThd) resulted in the formation of cyanoethyl and carboxyethyl
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The antagonist activity of N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate (N6MABP) has been examined at the phospholipase C-coupled P2Y1 receptor of turkey erythrocyte membranes. N6MABP antagonized 2MeSATP-stimulated inositol phosphate hydrolysis with a potency approximately 20 fold greater than the previously studied parent molecule
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我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
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