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GE17549111

HiTrap® MabSelect SuRe pcc

Cytiva 175491111, pkg of 5 × 1 mL

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About This Item

分類程式碼代碼:
41106500
NACRES:
NB.21

包裝

pkg of 5 × 1 mL

製造商/商標名

Cytiva 175491111

床高度 × 內徑 × 體積

(25 mm) (7 mm) (1 mL)

運輸包裝

ambient

儲存溫度

2-8°C

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一般說明

HiTrap MabSelect SuRe pcc chromatography columns are prepacked with MabSelect SuRe pcc protein A resin for screening and small-scale mAb purification in continuous bioprocessing using periodic counter-current chromatography (PCC).

  • Convenient prepacked column for fast, reproducible, and easy small-scale purifications.
  • High binding capacity, ~ 60 mg human IgG/mL resin at 2.4 min residence time
  • High productivity through capture of large mass of monoclonal antibodies in a short period of time.
  • Highly concentrated elution pools for operating flexibility and small unit operations.
  • Allows cost-effective cleaning with 0.1–0.5 M NaOH over hundreds of purification cycles.
  • High protein ligand stability reduces ligand leakage.

HiTrap MabSelect SuRe pcc packed columns (1 mL and 5 mL) are suited for small scale antibody purifications, as well as optimization of methods and parameters, such as sample load and protein binding conditions. These protein A columns provide fast, reproducible, and easy separations in a convenient format. The columns are optimally utilized when they are connected to liquid chromatography systems such as the ÄKTA systems.

MabSelect SuRe pcc affinity resin offers exceptional capacity at short residence time, making it well-suited for applications requiring fast mass transfer such as monoclonal antibody capture in a continuous process.

The alkali-stabilized, protein A-derived ligand gives the resin greater stability than conventional protein A-based resins under the alkaline conditions used in cleaning-in-place (CIP) protocols. Consequently, the possibility of cleaning with cost-effective reagents such as sodium hydroxide (NaOH) will improve process economy.

In addition, the use of NaOH for cleaning efficiently inactivates bacteria, mold, and yeast, with improved product quality as a result.

特點和優勢

  • Convenient prepacked column for Fast, reproducible, and easy small-scale purifications
  • High binding capacity, ~ 60 mg human IgG/mL resin at 2.4 min residence time
  • High productivity through capture of large mass of monoclonal antibodies in a short period of time
  • Highly concentrated elution pools for operating flexibility and small unit operations
  • Allows cost-effective cleaning with 0.1–0.5 M NaOH over hundreds of purification cycles
  • High protein ligand stability reduces ligand leakage

法律資訊

HiTrap is a registered trademark of Cytiva
MabSelect SuRe is a trademark of Cytiva

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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