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來源證明/COA

EHU049981

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human IDE

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About This Item

分類程式碼代碼:

41105324

NACRES:

NA.51

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Sigma-Aldrich

EMU164081

MISSION^® esiRNA

Sigma-Aldrich

BBO000578

2-Amino-4-methylquinoline hydrochloride

T234826

1-(TERT-BUTYLDIMETHYLSILYLOXY)-1,2,3,3A,5A,6-HEXAHYDROSPIRO[CYCLOPENTA[C]INDENE-4,2'-[1,3]DITHIAN]-7(5H)-ONE

Sigma-Aldrich

SAB4500105

Anti-TRIM38 antibody produced in rabbit

Sigma-Aldrich

CDS000027

3-Aminopropanamide hydrochloride

Sigma-Aldrich

8.14347

Lithium tetrafluoroborate

Z329681

BRAND^® wash bottle, wide-mouth, labelled, LDPE

Sigma-Aldrich

721530

Ethyl 2-oxopyrrolidine-3-carboxylate

Sigma-Aldrich

281026

四丁基六氟磷酸铵

Sigma-Aldrich

P5084

PTIO

描述

產品線

MISSION^®

形狀

lyophilized powder

esiRNA cDNA 標靶序列

TAACAATTTCCGGGCTGAACAGCCTCACCAGCATGCCATGTACTACCTCCGCTTGCTGATGACTGAAGTGGCCTGGACTAAAGATGAGTTAAAAGAAGCTCTGGATGATGTAACCCTTCCTCGCCTTAAGGCCTTCATACCTCAGCTCCTGTCACGGCTGCACATTGAAGCCCTTCTCCATGGAAACATAACAAAGCAGGCTGCATTAGGAATTATGCAGATGGTTGAAGACACCCTCATTGAACATGCTCATACCAAACCTCTCCTTCCAAGTCAGCTGGTTCGGTATAGAGAAGTTCAGCTCCCTGACAGAGGATGGTTTGTTTATCAGCAGAGAAATGAAGTTCACAATAACTGTGGCATCGAGATATACTACCAAACAGACATGCAAAGCACCTCAGA

Ensembl | 人類登錄號

ENSG00000119912

NCBI登錄號

NM_004969

運輸包裝

ambient

儲存溫度

−20°C

基因資訊

human ... IDE(3416) , IDE(3416)

一般說明

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律資訊

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Modulation of insulin degrading enzyme activity and liver cell proliferation.

Olga Pivovarova et al.

Cell cycle (Georgetown, Tex.), 14(14), 2293-2300 (2015-05-07)

Diabetes mellitus type 2 (T2DM), insulin therapy, and hyperinsulinemia are independent risk factors of liver cancer. Recently, the use of a novel inhibitor of insulin degrading enzyme (IDE) was proposed as a new therapeutic strategy in T2DM. However, IDE inhibition

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MISSION^® esiRNA