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E125

Sigma-Aldrich

β-雌二醇

同義詞:

17β-雌二醇, 1,3,5-雌三烯-3,17β-二醇, 3,17β-二羟基-1,3,5(10)-雌三烯, 二氢卵泡素

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About This Item

經驗公式(希爾表示法):
C18H24O2
CAS號碼:
分子量::
272.38
Beilstein:
1914275
EC號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

mp

176-180 °C (lit.)

儲存溫度

2-8°C

SMILES 字串

O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C

InChI

1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

InChI 密鑰

VOXZDWNPVJITMN-ZBRFXRBCSA-N

基因資訊

human ... ESR1(2099)

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生化/生理作用

绝经前卵巢分泌的主要雌激素。雌激素通过调节基因转录并因此调节蛋白质合成来指导胚胎发生和青春期女性表型的发展。 它还诱导促性腺激素的产生,进而诱导排卵。 暴露于雌二醇会增加乳腺癌的发生率和增殖。

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產品號碼
描述
訂價

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

188.6 °F

閃點(°C)

87 °C

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


分析證明 (COA)

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Nature chemical biology, 5(8), 585-592 (2009-06-30)
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James S Wright et al.
Journal of medicinal chemistry, 54(2), 433-448 (2010-12-31)
Long-term use of estrogen supplements by women leads to an increased risk of breast and uterine cancers. Possible mechanisms include metabolism of estradiol and compounds related to tumor-initiating quinones, and ligand-induced activation of the estrogen receptors ERα and ERβ which
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