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Merck
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文件

C5820

Sigma-Aldrich

Chondroitin disaccharide Δdi-UA-2S sodium salt

同義詞:

α-ΔUA-2S-[1→3]-GalNAc

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About This Item

線性公式:
C14H19NO14SNa2
CAS號碼:
分子量::
503.34
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:

生物源

synthetic

化驗

≥98% (HPLC)

形狀

powder

技術

HPLC: suitable

儲存溫度

−20°C

SMILES 字串

[Na].CC(=O)NC(C=O)C(OC1OC(=CC(O)C1OS(O)(=O)=O)C(O)=O)C(O)C(O)CO

InChI

1S/C14H21NO14S.Na.H/c1-5(18)15-6(3-16)11(10(21)8(20)4-17)28-14-12(29-30(24,25)26)7(19)2-9(27-14)13(22)23;;/h2-3,6-8,10-12,14,17,19-21H,4H2,1H3,(H,15,18)(H,22,23)(H,24,25,26);;

InChI 密鑰

RZWFDDVYBLJQSX-UHFFFAOYSA-N

應用

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

其他說明

ΔUA = 4-deoxy-L-threo-hex-4-enopyranosyluronic acid; GalNAc = N-acetyl-D-galactosamine; 2S = 2-sulfate

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析證明 (COA)

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The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system.
Galtrey CM, Fawcett JW.
Brain Research. Brain Research Reviews, 54, 1-18 (2007)
J C F Kwok et al.
The international journal of biochemistry & cell biology, 44(4), 582-586 (2012-01-24)
Chondroitin sulfate is a glycosaminoglycan composed of N-acetylgalactosamine and glucuronic acid. It attaches to a core protein to form chondroitin sulfate proteoglycan (CSPG). Being a major component of the brain extracellular matrix, CSPGs are involved in neural development, axon pathfinding
Yulin Li et al.
Chemical Society reviews, 41(6), 2193-2221 (2011-11-26)
Injectable hydrogels with biodegradability have in situ formability which in vitro/in vivo allows an effective and homogeneous encapsulation of drugs/cells, and convenient in vivo surgical operation in a minimally invasive way, causing smaller scar size and less pain for patients.
Wen-Li Gu et al.
Sheng li ke xue jin zhan [Progress in physiology], 38(2), 101-105 (2007-07-18)
Chondroitin sulfate proteoglycans (CSPGs) are major components of extracellular matrix in the central nervous system (CNS) , and play important roles in the development and maintenance of CNS, as welt in pathogenesis or repair processes of neuronal damages. They mainly
Juliane Salbach et al.
Journal of molecular medicine (Berlin, Germany), 90(6), 625-635 (2011-12-22)
To meet the growing need for tissue replacement materials for our aging population, the development of new adaptive biomaterials is essential. The tissues with the highest demand for implant materials are skin and bone. These tissues share various similarities, including

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