ABN201

Anti-CYP24A1 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 24-OHase, Vitamin D(3) 24-hydroxylase, Cytochrome P450 24A1, Cytochrome P450-CC24
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: immunohistochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_000773
• UniProt登錄號: Q07973
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CYP24A1(1591)

描述

一般說明

Also known as Vitamin D(3) 24-hydroxylase, CYP24A1 is a member of the cytochrome P450 (CYP) family of enzymes. Most members of the CYP family can metabolize multiple substrates, and can catalyze multiple reactions. The CYP24A1 is a mitochondrial protein that starts the breakdown of 1,25-dihydrozyvitamin D3 by hydroxylation of the side chain to form calcitroic acid. This enzyme also has a role in calcium homeostasis and the vitamin D endocrine system.

特異性

Other Homologies: Bovine (92% sequence homology) and Rat (75% sequence homology).

免疫原

KLH-conjugated linear peptide corresponding to human CYP24A1.

應用

Anti-CYP24A1 Antibody is an antibody against CYP24A1 for use in 0.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

品質

Evaluated by Western Blot in A549 cell lysate.

Western Blot Analysis: 0.2 µg/mL of this antibody detected CYP24A1 in 10 µg of A549 cell lysate.

標靶描述

~60 kDa observed. Two isoforms are known to exist at 59 kDa and 51 kDa This antibody is expected to recognize both isoforms.

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
A549 cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable