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Key Documents

AB5495

Sigma-Aldrich

Anti-Potassium Channel Kir6.2 Antibody

Chemicon®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

affinity purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

純化經由

affinity chromatography

物種活性

rat

製造商/商標名

Chemicon®

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... KCNJ11(3767)

特異性

Recognizes Kir6.2 (Inward rectifier potassium channel Kir6.2). The antibody does not react with Kir6.1. The epitope specific for Kir6.2 is not present in any other known proteins.

免疫原

Highly purified peptide corresponding to residues 372-385 of rat Kir6.2 (Accession P70673). The immunogen sequence is identical in mouse and conserved in human (12/14).

應用

Anti-Potassium Channel Kir6.2 Antibody detects level of Potassium Channel Kir6.2 & has been published & validated for use in WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blotting: 1:200 using ECL on rat pancreas lysate.

Immunohistochemistry on rat pancrease sections. Dilutions should be made using a carrier protein such as BSA (1-3%).

Optimal working dilutions must be determined by the end user.

外觀

Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.025% sodium azide. Reconstitute with 50 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).

儲存和穩定性

Maintain lyophilized material at -20°C for up to 6 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

分析報告

Control
Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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危險聲明

防範說明

危險分類

Aquatic Chronic 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

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Frontiers in cellular neuroscience, 8, 255-255 (2014-09-16)
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Andrew G Edwards et al.
The Journal of physiology, 587(Pt 23), 5723-5737 (2009-10-07)
The female myocardium, relative to that of the male, exhibits sustained resistance to ischaemic tissue injury, a phenomenon termed sex-specific cardioprotection (SSC). SSC is dependent upon the sarcolemmal K(ATP) channel (sarcK(ATP)), and protein kinase C (PKC). Here we investigate whether
Atsuko Miura et al.
The Journal of biological chemistry, 281(8), 5246-5257 (2005-12-27)
Mutations in the hepatocyte nuclear factor (HNF)-4alpha gene cause a form of maturity-onset diabetes of the young (MODY1) that is characterized by impairment of glucose-stimulated insulin secretion by pancreatic beta-cells. HNF-4alpha, a transcription factor belonging to the nuclear receptor superfamily
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British journal of pharmacology, 172(18), 4519-4534 (2015-07-04)
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