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Merck
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Key Documents

14-683-M

Sigma-Aldrich

PAK3 Protein, active, 10 µg

Active, C-terminal 6His-tagged, recombinant, human full length, PAK3. For use in Kinase Assays.

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About This Item

分類程式碼代碼:
12352202
eCl@ss:
32160405
NACRES:
NA.32

生物源

human

品質等級

100
300

重組細胞

expressed in baculovirus infected Sf21 cells

分子量

Mw 63.2 kDa

製造商/商標名

Upstate®

技術

activity assay: suitable (kinase)

NCBI登錄號

UniProt登錄號

基因資訊

human ... PAK3(5063)

一般說明

C-terminal 6His-tagged, recombinant, human full length, PAK3.

mitosis
Product Source: PAK3 expressed by baculovirus in Sf21 cells.

應用

Research Category
Inflammation & Immunology

生化/生理作用

Protein Target: PAK3
Target Sub-Family: STE

品質

routinely evaluated by phosphorylation of PAKtide (RRRLSFAEPG).

外觀

Ni2+/NTA-agarose

儲存和穩定性

6 months at -70°C from date of shipment

其他說明

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Skin Sens. 1

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Rho proteins, mental retardation and the neurobiological basis of intelligence.
van Galen, Elly J M and Ramakers, Ger J A
Progress in Brain Research, 147, 295-317 (2005)
J Roig et al.
Vitamins and hormones, 62, 167-198 (2001-05-11)
The p21-activated protein kinase gamma-PAK, also known as PAK2, has very different properties from the other two highly conserved isoforms of the PAK family, alpha-PAK (PAK1) and beta-PAK (PAK3). gamma-PAK has cytostatic activity, as shown by inhibition of cleavage of
Ger J A Ramakers
Trends in neurosciences, 25(4), 191-199 (2002-05-10)
For several decades, it has been known that mental retardation (MR) is associated with abnormalities in dendrites and dendritic spines. The recent cloning of seven genes that cause nonspecific MR when mutated provides important insights in the cellular mechanisms that
Zahara M Jaffer et al.
The international journal of biochemistry & cell biology, 34(7), 713-717 (2002-04-16)
The p21-activated kinases (Paks) are serine/threonine protein kinases that bind to and, in some cases, are stimulated by activated forms of the small GTPases, Cdc42 and Rac. With the recent discovery of several novel isoforms, Paks are now categorized into

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