137151

2-巯基乙醇

EMPROVE^® EVOLVE

• 同義詞: β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇
• 線性公式: HSCH₂CH₂OH
• CAS號碼: 60-24-2
• 分子量：: 78.13
• Beilstein: 773648
• MDL號碼: MFCD00004890
• 分類程式碼代碼: 12161504

屬性

• 蒸汽密度: 2.69 (vs air)
• 品質等級: 400
• 蒸汽壓力: 1 mmHg ( 20 °C)
• 形狀: liquid
• expl. lim.: 18 %
• 濃度: 14.3 M (pure liquid); 99.0-101.0 % (w/w)
• 雜質: ≤1.0% related substances (GC) 2,2-Dithiodiethanol
• 折射率: n20/D 1.500 (lit.)
• bp: 157 °C (lit.)
• 密度: 1.114 g/mL at 25 °C (lit.)
• 適合性: corresponds for identity (IR)
• 應用: pharma/biopharma processes
• 儲存溫度: 2-8°C
• SMILES 字串: OCCS
• InChI: 1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
• InChI 密鑰: DGVVWUTYPXICAM-UHFFFAOYSA-N

描述

一般說明

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

As part of our EMPROVE^® Program, our raw materials are offered with EMPROVE^® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

應用

BME 适用于在聚丙烯酰胺凝胶电泳前还原蛋白质二硫键，通常用于 SDS-PAGE 的样品缓冲液，浓度为 5%。 切割分子间（亚基之间）二硫键允许蛋白质的亚基在 SDS-PAGE 上独立分离。 切割分子内（亚基内）二硫键可使亚基完全变性，从而使每个肽根据其链长迁移，而不受二级结构的影响。

分析報告

purity (GC) ≥99.0%

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS05,GHS06,GHS08,GHS09
• 訊號詞: Danger
• 危險聲明: H301 + H331 - H310 - H315 - H317 - H318 - H361fd - H373 - H410
• 防範說明: P201 - P260 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P305 + P351 + P338 + P310
• 危險分類: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral
• 儲存類別代碼: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• 水污染物質分類（WGK）: WGK 3
• 閃點（°C）: 74 °C - closed cup