06-018

Anti-ROR2 Antibody, CT

from rabbit

• 同義詞: Neurotrophic tyrosine kinase, receptor-related 2, neurotrophic tyrosine kinase receptor-related 2, receptor tyrosine kinase-like orphan receptor 2, tyrosine-protein kinase transmembrane receptor ROR2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: human
• 技術: immunohistochemistry: suitable (paraffin)
• NCBI登錄號: NP_004551.2
• UniProt登錄號: Q01974
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... ROR2(4920)

描述

一般說明

Receptor tyrosine kinase-like orphan receptor 2, also known as ROR2, is a member of the Tyr protein kinase family and ROR subfamily of cell surface receptors. Located in the transmembrane, ROR2 is highly expressed during early embryonic development and is associated with chondrocyte formation, cartilage and growth plate maturity. Expression levels of ROR2 subside after 16 days and occur minimally in adults. ROR2 is post translationaly modified by ATM or ATR phosphorylation when DNA damage occurs. Mutations in ROR2 result in brachydactyly type B1 (BDB1), characterized by either hypoplasia or aplasia of the distal phalanges and nails. ROR2 is also associated with recessive Robinow syndrome (RRS), resulting in shortening of limbs, facial dysmorphia and spinal defects.

特異性

This antibody recognizes the C-terminal region of ROR2.

免疫原

Epitope: C-terminus

KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of ROR2

應用

Anti-ROR2 Antibody, C-terminus detects level of ROR2 & has been published & validated for use in IH(P).

Research Category
Inflammation & Immunology

Research Sub Category
Immunological Signaling

品質

Evaluated by immunohistochemistry (paraffin) in human gastric mucosa.

Immunohistochemistry(paraffin): 1:50-1:200 dilution of this antibody detected ROR2 in human gastric mucosa.

標靶描述

~105 kDa

外觀

Protein G Purified

Format: Purified

Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8ºC from date of receipt.

分析報告

Control
Human gastric mucosa

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable