推薦產品
等級
certified reference material
品質等級
形狀
liquid
特點
Snap-N-Spike®/Snap-N-Shoot®
包裝
ampule of 1 mL
製造商／商標名
Cerilliant®
濃度
100 μg/mL in methanol (as free phosphate)
技術
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
應用
forensics and toxicology
格式
single component solution
儲存溫度
−70°C
一般說明
This stable-labeled internal standard is suitable for quantitation of PEth 16:0/18:1 in LC/MS or GC/MS applications. PEth 16:0/18:1, also known as phosphatidylethanol 16:0/18:1, is a sensitive and specific biomarker for alcohol use and abuse. Since the detection window of PEth 16:0/18:1 in blood is longer than that of ethyl glucuronide (EtG) or ethyl sulfate (EtS) in urine, measurement of blood PEth 16:0/18:1 level is routinely performed in clinical toxicology and forensic testing applications such as abstinence monitoring and workplace drug testing. PEth 16:0/18:1 has also been investigated as a biomarker to confirm prenatal alcohol exposure (PAE).
應用
- Validation of LC-MS/MS method for erythrocyte phosphatidylethanol: A recent study validated a liquid chromatography tandem mass spectrometry method for erythrocyte phosphatidylethanol (PEth), utilizing the PEth 16:0/18:1-D₅ internal standard. This research highlights critical considerations for using PEth as a reliable clinical biomarker of alcohol consumption, proving essential for advancements in biochemical research reagents and methodology (White et al., 2022).
法律資訊
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
標靶器官
Eyes
儲存類別代碼
3 - Flammable liquids
閃點（°F）
49.5 °F - closed cup
閃點（°C）
9.7 °C - closed cup
分析證明 (COA)
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