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878114P

Avanti

C18-02:0 PC

Avanti Research - A Croda Brand 878114P, powder

同義詞:

1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine

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About This Item

經驗公式(希爾表示法):
C28H58NO7P
CAS號碼:
分子量::
551.74
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 1 × 5 mg (878114P-5mg)

製造商/商標名

Avanti Research - A Croda Brand 878114P

脂質類型

bioactive lipids
phosphoglycerides

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C)=O)COCCCCCCCCCCCCCCCCCC)=O

InChI

1S/C28H58NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-23-33-25-28(36-27(2)30)26-35-37(31,32)34-24-22-29(3,4)5/h28H,6-26H2,1-5H3/t28-/m1/s1

InChI 密鑰

ZXCIEWBDUAPBJF-MUUNZHRXSA-N

一般說明

C18-02:0 PC, also referred as 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine, is a natural platelet-activating factor. It is found in variety of cells including, basophil leucocytes, macrophages, polymorphonuclear neutrophils and monocytes and platelets.

應用

C18-02:0 PC or 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine may be used as a substrate in enzymatic lipoprotein-associated phospholipase A2 (Lp-PLA2) activity assay.

生化/生理作用

C18-02:0 PC acts as a platelet-activating factor and facilitates platelet aggregation and secretion. It also plays a key role in inflammation and anaphylaxis.

包裝

5 mL Clear Glass Sealed Ampule (878114P-5mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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Scott D Ryan et al.
Journal of lipid research, 49(10), 2250-2258 (2008-06-14)
The platelet-activating factor (PAF) family of glycerophospholipids accumulates in damaged brain tissue following injury. Little is known about the role of individual isoforms in regulating neuronal survival. Here, we compared the neurotoxic and neuroprotective activities of 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16-PAF) and 1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
Saki Yamaura et al.
Clinica chimica acta; international journal of clinical chemistry, 481, 184-188 (2018-03-20)
Measurement of lipoprotein-associated phospholipase A2 (Lp-PLA2) can be used as an adjunct to traditional cardiovascular risk factors for identifying individuals at higher risk of cardiovascular events. This can be performed by quantification of the protein concentration using an ELISA platform

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