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化驗
99%
光學活性
[α]24/D +23.6°, c = 4 in 6 M HCl
mp
245 °C (dec.) (lit.)
SMILES 字串
Cl.NCCC[C@H](N)C(O)=O
InChI
1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
InChI 密鑰
GGTYBZJRPHEQDG-WCCKRBBISA-N
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Sherry Dadsetan et al.
Biochemical pharmacology, 85(1), 115-123 (2012-10-30)
Combined administration of ornithine and phenylacetate (OP) is proposed as a novel treatment of hyperammonemia and hepatic encephalopathy. Ornithine is believed to increase ammonia fixation into glutamine in muscle tissue and glutamine is subsequently thought to react with phenylacetate forming
Charles D Mills
Critical reviews in immunology, 32(6), 463-488 (2013-02-23)
The purpose of immunology is simple. Cure or prevent disease. M1/M2 is useful because it is simple. M1/M2 describes the two major and opposing activities of macrophages. M1 activity inhibits cell proliferation and causes tissue damage while M2 activity promotes
Takuya Ouchi et al.
Nature chemical biology, 9(4), 277-283 (2013-02-26)
LysW has been identified as a carrier protein in the lysine biosynthetic pathway that is active through the conversion of α-aminoadipate (AAA) to lysine. In this study, we found that the hyperthermophilic archaeon, Sulfolobus acidocaldarius, not only biosynthesizes lysine through
Shawn Elms et al.
American journal of physiology. Heart and circulatory physiology, 305(5), H651-H666 (2013-06-25)
Reduced production of nitric oxide (NO) is one of the first indications of endothelial dysfunction and precedes overt cardiovascular disease. Increased expression of Arginase has been proposed as a mechanism to account for diminished NO production. Arginases consume l-arginine, the
Nicole Berthold et al.
Antimicrobial agents and chemotherapy, 57(1), 402-409 (2012-11-02)
Proline-rich antimicrobial peptides (PrAMPs) from insects and mammals have recently been evaluated for their pharmaceutical potential in treating systemic bacterial infections. Besides the native peptides, several shortened, modified, or even artificial sequences were highly effective in different murine infection models.
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