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Key Documents

284122

Sigma-Aldrich

5-胆甾烯-3β-醇-7-酮

95%

同義詞:

3β-羟基-5-胆甾烯-7-酮, 7-酮基胆固醇

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About This Item

經驗公式(希爾表示法):
C27H44O2
CAS號碼:
分子量::
400.64
MDL號碼:
分類程式碼代碼:
12352103
PubChem物質ID:

化驗

95%

SMILES 字串

C[C@]12CC[C@@]([C@](CC[C@H](O)C3)(C)C3=CC4=O)([H])[C@]4([H])[C@]1([H])CC[C@]2([H])[C@]([H])(C)CCCC(C)C

InChI

1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,25+,26+,27-/m1/s1

InChI 密鑰

YIKKMWSQVKJCOP-ABXCMAEBSA-N

尋找類似的產品? 前往 產品比較指南

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Jiahn-Dar Huang et al.
Biochimica et biophysica acta, 1821(4), 637-646 (2012-02-22)
Sterculic acid is a cyclopropene fatty acid with numerous biological activities. In this study we demonstrate that sterculic acid is a potent inhibitor of endoplasmic reticulum (ER) stress and related inflammation caused by 7-ketocholesterol (7KCh). 7KCh is a highly toxic
Vesa M Olkkonen
Current opinion in lipidology, 23(5), 462-470 (2012-07-21)
To offer a comprehensive review on the roles that oxysterols synthesized or engulfed by macrophages, or oxysterol-binding proteins in these cells, play in the development and progression of atherosclerotic lesions. Oxysterols abundant within the plaque have the capacity to potentiate
Luisa Tesoriere et al.
The British journal of nutrition, 110(2), 230-240 (2012-12-12)
7-Ketocholesterol (7-KC)-induced apoptosis of macrophages is considered a key event in the development of human atheromas. In the present study, the effect of indicaxanthin (Ind), a bioactive pigment from cactus pear fruit, on 7-KC-induced apoptosis of human monocyte/macrophage THP-1 cells
Dmitri Svistounov et al.
PloS one, 7(9), e46134-e46134 (2012-10-03)
Fenestrations are transcellular pores in endothelial cells that facilitate transfer of substrates between blood and the extravascular compartment. In order to understand the regulation and formation of fenestrations, the relationship between membrane rafts and fenestrations was investigated in liver sinusoidal
Rodrigo T Iborra et al.
Lipids in health and disease, 10, 172-172 (2011-10-01)
Advanced glycation end products (AGE) alter lipid metabolism and reduce the macrophage expression of ABCA-1 and ABCG-1 which impairs the reverse cholesterol transport, a system that drives cholesterol from arterial wall macrophages to the liver, allowing its excretion into the

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