化驗
99%
mp
220 °C (dec.) (lit.)
SMILES 字串
NS(=O)(=O)c1cc(C(O)=O)c(NCc2ccco2)cc1Cl
InChI
1S/C12H11ClN2O5S/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19/h1-5,15H,6H2,(H,16,17)(H2,14,18,19)
InChI 密鑰
ZZUFCTLCJUWOSV-UHFFFAOYSA-N
基因資訊
human ... SLC12A1(6557)
尋找類似的產品？ 前往 產品比較指南
生化／生理作用
抑制肾脏中离子的协同运输。
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
Diane Joseph-McCarthy et al.
Journal of medicinal chemistry, 48(25), 7960-7969 (2005-12-13)
Acyl carrier protein synthase (AcpS) catalyzes the transfer of the 4'-phosphopantetheinyl group from the coenzyme A to a serine residue in acyl carrier protein (ACP), thereby activating ACP, an important step in cell wall biosynthesis. The structure-based design of novel
Hanne H F Refsgaard et al.
Journal of medicinal chemistry, 48(3), 805-811 (2005-02-04)
A data set consisting of 712 compounds was used for classification into two classes with respect to membrane permeation in a cell-based assay: (0) apparent permeability (P(app)) below 4 x 10(-6) cm/s and (1) P(app) on 4 x 10(-6) cm/s
Paul J Gilligan et al.
Journal of medicinal chemistry, 52(9), 3084-3092 (2009-04-14)
This report describes the syntheses and structure-activity relationships of 8-(substituted pyridyl)pyrazolo[1,5-a]-1,3,5-triazine corticotropin releasing factor receptor-1 (CRF(1)) receptor antagonists. These CRF(1) receptor antagonists may be potential anxiolytic or antidepressant drugs. This research resulted in the discovery of compound 13-15, which is
Claudia Temperini et al.
Bioorganic & medicinal chemistry letters, 18(8), 2567-2573 (2008-04-01)
Diuretics such as hydrochlorothiazide, hydroflumethiazide, quinethazone, metolazone, chlorthalidone, indapamide, furosemide, and bumetanide containing primary sulfamoyl moieties were reevaluated as inhibitors of 12 human carbonic anhydrases (hCAs, EC 4.2.1.1). These drugs considerably inhibit (low nanomolar range) some CA isozymes involved in
Godfrey Lisk et al.
Antimicrobial agents and chemotherapy, 52(7), 2346-2354 (2008-04-30)
Cysteine protease inhibitors kill malaria parasites and are being pursued for development as antimalarial agents. Because they have multiple targets within bloodstream-stage parasites, workers have assumed that resistance to these inhibitors would not be acquired easily. In the present study
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務