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143413

Sigma-Aldrich

1,3-二氨基胍 单盐酸盐

98%

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About This Item

線性公式:
H2NNHC(=NH)NHNH2·HCl
CAS號碼:
分子量::
125.56
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

mp

180-182 °C (dec.) (lit.)

溶解度

water: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

SMILES 字串

Cl.NNC(=N)NN

InChI

1S/CH7N5.ClH/c2-1(5-3)6-4;/h3-4H2,(H3,2,5,6);1H

InChI 密鑰

HAZRIBSLCUYMQP-UHFFFAOYSA-N

一般說明

1,3-二氨基胍盐酸盐可用于以下缩合反应:
  • 与4-異硫氰酸-4-甲基戊烷-2-酮反应生成缩合嘧啶
  • 与各种醛和酮反应生成双胍类衍生物

其他說明

含氯化钠

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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J Brimnes et al.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 107(6), 555-565 (1999-06-24)
Several N-N-and N-O-containing compounds were analysed for their ability to act as substrates for horseradish peroxidase and peroxidases in Mycobacterium tuberculosis extracts. Aminoguanidine, diaminoguanidine, isoniazid, hydroxylamine and hydrazine were found to be weak substrates for horseradish peroxidase in reaction I
Synthesis of condensed pyrimidines and their evaluation for anti-inflammatory and analgesic activities.
Sondhi SM, et al.
Indian J. Chem. B, 47(1), 136-136 (2008)
Synthesis of biologically active novel bis Schiff bases, bis hydrazone and bis guanidine derivatives.
Sondhi SM, et al.
Indian J. Chem. B, 48(8), 1128-1128 (2009)
Anthony J Lee et al.
Chemical research in toxicology, 18(12), 1927-1933 (2005-12-20)
It is established that aminoguanidine (AG), diaminoguanidine (DAG), and NG-amino-l-arginine (NAA) are metabolism-based inactivators of the three major isoforms of nitric oxide synthase (NOS). In the case of neuronal NOS (nNOS), heme alteration is known to be a major cause
D Dvornik et al.
Journal of diabetes and its complications, 10(1), 23-30 (1996-01-01)
Aminoguanidine, nucleophilic hydrazine derivative, has been shown to inhibit diamine oxidase, the formation of advanced glycation endproducts, nitric oxide synthase, and catalase. Prompted by the reports that aminoguanidine also inhibits aldose reductase (AR), we have investigated the effect of aminoguanidine

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