TRIB2
tribbles homolog 2 (Drosophila)
同義詞:
C5FW, GS3955, TRB2
物種:
Human TRIB2 (28951), Mouse Trib2 (217410), Rat Trib2 (313974), domestic cat TRIB2 (101085367), sheep TRIB2 (101121332), Domestic Rabbit TRIB2 (100357208), domestic guinea pig Trib2 (100718073), naked mole-rat Trib2 (101720665), Zebrafish trib2 (100331041), chicken TRIB2 (378919) ...更多
UniProtKB ID:
基因 ID:
- Human(28951) Summary: This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]
- Mouse(217410) tribbles homolog 2 (Drosophila)
- Rat(313974) tribbles homolog 2 (Drosophila)
- domestic cat(101085367) tribbles homolog 2 (Drosophila)
- sheep(101121332) tribbles homolog 2 (Drosophila)
- Domestic Rabbit(100357208) tribbles homolog 2 (Drosophila)
- domestic guinea pig(100718073) tribbles homolog 2 (Drosophila)
- naked mole-rat(101720665) tribbles homolog 2 (Drosophila)
- Zebrafish(100331041) tribbles homolog 2 (Drosophila)
- chicken(378919) tribbles homolog 2 (Drosophila)
- dog(403884) tribbles homolog 2 (Drosophila)
- cow(352960) tribbles homolog 2 (Drosophila)
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Antibodies
產品編號
描述
物種活性
應用
Anti-TRIB2 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot