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Merck

TNFSF12

tumor necrosis factor (ligand) superfamily, member 12

同義詞:
APO3L, DR3LG, TWEAK
物種:
Human TNFSF12 (8742), Mouse Tnfsf12 (21944), Rat Tnfsf12 (360548), domestic guinea pig Tnfsf12 (100713543), domestic cat TNFSF12 (101098755), Zebrafish tnfsf12 (567542), dog TNFSF12 (100568280), cow TNFSF12 (100568284), cow TNFSF12 (100551513), Domestic Rabbit TNFSF12 (100356651) ...更多
UniProtKB ID:
O43508, Q8IZK7, Q8WUZ7
基因 ID:
  • Human(8742) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tissue distribution. This cytokine, which exists in both membrane-bound and secreted forms, can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. This cytokine is also found to promote proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. Alternative splicing results in multiple transcript variants. Some transcripts skip the last exon of this gene and continue into the second exon of the neighboring TNFSF13 gene; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
  • Mouse(21944) tumor necrosis factor (ligand) superfamily, member 12
  • Rat(360548) tumor necrosis factor ligand superfamily member 12
  • domestic guinea pig(100713543) tumor necrosis factor (ligand) superfamily, member 12
  • domestic cat(101098755) tumor necrosis factor (ligand) superfamily, member 12
  • Zebrafish(567542) tumor necrosis factor (ligand) superfamily, member 12
  • dog(100568280) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100568284) tumor necrosis factor (ligand) superfamily, member 12
  • cow(100551513) tumor necrosis factor (ligand) superfamily, member 12
  • Domestic Rabbit(100356651) tumor necrosis factor (ligand) superfamily, member 12
  • Horse(100061872) tumor necrosis factor (ligand) superfamily, member 12
  • sheep(101122801) tumor necrosis factor (ligand) superfamily, member 12

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Antibodies

產品編號
描述
物種活性
應用
HPA052967
Anti-TNFSF12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry

Proteins

產品編號
描述
物種
GF102
TWEAK，人类, Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis.,
物種
human