TGFB2
transforming growth factor, beta 2
同義詞:
LDS4, TGF-beta2
物種:
Human TGFB2 (7042), Mouse Tgfb2 (21808), Rat Tgfb2 (81809), dog TGFB2 (488596), Zebrafish tgfb2 (369194), domestic guinea pig Tgfb2 (100720726), chicken TGFB2 (421352), cow TGFB2 (534069), domestic cat TGFB2 (101093414), sheep TGFB2 (554322) ...更多
UniProtKB ID:
基因 ID:
- Human(7042) Summary: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010]
- Mouse(21808) transforming growth factor, beta 2
- Rat(81809) transforming growth factor, beta 2
- dog(488596) transforming growth factor, beta 2
- Zebrafish(369194) transforming growth factor, beta 2
- domestic guinea pig(100720726) transforming growth factor, beta 2
- chicken(421352) transforming growth factor, beta 2
- cow(534069) transforming growth factor, beta 2
- domestic cat(101093414) transforming growth factor, beta 2
- sheep(554322) transforming growth factor, beta 2
- Domestic Rabbit(100009371) transforming growth factor, beta 2
- naked mole-rat(101707457) transforming growth factor, beta 2
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ELISA
產品編號
描述
物種
Antibodies
產品編號
描述
物種活性
應用
Anti-TGFB2 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, horse, human, mouse, pig, rabbit, rat, sheep
應用
western blot
Anti-TGF β2, C-Terminal antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
immunohistochemistry
ANTI-TGF BETA 2(C-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human
應用
immunohistochemistry
western blot
western blot
抗-转化生长因子-β，pan 兔抗, IgG fraction of antiserum, lyophilized powder,
物種活性
amphibian, human, pig
應用
microarray
neutralization
western blot
neutralization
western blot
Proteins
產品編號
描述
物種
Transforming Growth Factor-β2 human, TGF-β2, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture,
物種
human
重组人转化生长因子-β2蛋白, Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.,
物種
human
Transforming Growth Factor-β2 human, TGF-β2, recombinant, expressed in NSO cells, powder, suitable for cell culture,
物種
human