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Merck

SMAD4

SMAD family member 4

同義詞:
DPC4, JIP, MADH4, MYHRS
物種:
Human SMAD4 (4089), Mouse Smad4 (17128), Rat Smad4 (50554), dog SMAD4 (476196), domestic cat SMAD4 (101093650), Zebrafish smad4 (30640), domestic guinea pig Smad4 (100717853), naked mole-rat Smad4 (101703764), sheep SMAD4 (443171), cow SMAD4 (540248) ...更多
UniProtKB ID:
Q13485, A8K405
基因 ID:
  • Human(4089) Summary: This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009]
  • Mouse(17128) SMAD family member 4
  • Rat(50554) SMAD family member 4
  • dog(476196) SMAD family member 4
  • domestic cat(101093650) SMAD family member 4
  • Zebrafish(30640) MAD homolog 4 (Drosophila)
  • domestic guinea pig(100717853) SMAD family member 4
  • naked mole-rat(101703764) SMAD family member 4
  • sheep(443171) SMAD family member 4
  • cow(540248) SMAD family member 4
  • Horse(100033846) SMAD family member 4
  • Goat(100861019) SMAD family member 4

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Antibodies

產品編號
描述
物種活性
應用
HPA019154
Anti-SMAD4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human, mouse
應用
immunofluorescence
immunohistochemistry
western blot
SAB5300375
Monoclonal Anti-SMAD4 antibody produced in mouse, clone 4G1C6, ascites fluid,
物種活性
human
應用
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
SAB2102232
Anti-SMAD4 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, goat, guinea pig, horse, human, mouse, rabbit, rat, sheep
應用
immunohistochemistry
western blot
ABE21
Anti-Smad4/DPC4 Antibody, from rabbit, purified by affinity chromatography,
物種活性
chimpanzee, human, mouse, rat
應用
immunocytochemistry
western blot
SAB1412182
ANTI-SMAD4 antibody produced in mouse, clone 3D7, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
proximity ligation assay
western blot

Proteins

產品編號
描述
物種
SRP5133
SMAD4, GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human

esiRNA

產品編號
描述
物種
EHU018671
MISSION® esiRNA, targeting human SMAD4,
物種
human