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Merck

SLC6A4

solute carrier family 6 (neurotransmitter transporter), member 4

同義詞:
5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT
物種:
UniProtKB ID:
基因 ID:
  • Human(6532) Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq, Jul 2008]
  • Mouse(15567) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Rat(25553) solute carrier family 6 (neurotransmitter transporter), member 4
  • domestic guinea pig(100135619) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • naked mole-rat(101705584) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100340600) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Domestic Rabbit(100351801) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • dog(491184) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • domestic cat(101091163) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • Horse(100053721) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • cow(282365) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
  • chicken(404747) solute carrier family 6 (neurotransmitter transporter, serotonin), member 4

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Small Molecule - Antagonist

產品編號
描述
物種
N -乙基马来酰亚胺, purum p.a., ≥99.0% (HPLC),
物種
human
N -乙基马来酰亚胺, BioUltra, ≥99.0% (HPLC),
物種
human
4-苄基吡啶, 98%,
物種
rat
N -乙基马来酰亚胺, BioXtra, ≥98% (HPLC),
物種
human
二苯基-4-吡啶基甲烷, 99%,
物種
rat

Antibodies

產品編號
描述
物種活性
應用
Anti-Serotonin Transporter (N-terminal) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
western blot
Anti-Serotonin (5-HT) Transporter (602-622) Rabbit pAb, lyophilized, Calbiochem®,
物種活性
mouse, rat
應用
Anti-SLC6A4/5HTT/SERT antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
Anti-SLC6A4 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
bovine, human, mouse, rat
應用
ELISA
flow cytometry

immunofluorescence
Monoclonal Anti-SLC6A4 antibody produced in mouse, clone 2A9, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA

Small Molecule - Inhibitor

產品編號
描述
物種
艾司西酞普兰 草酸酯, ≥98% (HPLC), powder,
物種
human
帕罗西汀 盐酸盐 半水合物, ≥98% (HPLC), powder,
物種
human
氟西汀盐酸盐, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
氟西汀 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
达泊西汀 盐酸盐, ≥98% (HPLC),
物種
human

Small Molecule - Ligand

產品編號
描述
物種
可卡因 游离碱, ,
物種
mouse, rat, human