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Merck

SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

同義詞:
NAT1, NET, NET1, SLC6A5
物種:
Human SLC6A2 (6530), Mouse Slc6a2 (20538), Rat Slc6a2 (83511), domestic guinea pig Slc6a2 (100723578), naked mole-rat Slc6a2 (101716834), sheep SLC6A2 (101116078), sheep SLC6A2 (443100), Domestic Rabbit SLC6A2 (100328959), dog SLC6A2 (487272), domestic cat SLC6A2 (101099605) ...更多
UniProtKB ID:
P23975, B2R707, Q96KH8
基因 ID:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

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Small Molecule - Antagonist

產品編號
描述
物種
32950
4,4′-二氨基二苯甲烷, ≥97.0% (GC),
物種
mouse, rat
N5536
Nefazodone hydrochloride, ≥98% (HPLC), solid,
物種
human
A-123
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
物種
human
PHR1841
阿莫沙平, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
A129
Amoxapine, ,
物種
human

Antibodies

產品編號
描述
物種活性
應用
SAB2108224
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot
MAB5620
Anti-Norepinephrine Transporter Antibody, ascites fluid, Chemicon®,
物種活性
human, monkey
應用
immunohistochemistry
AB5066P
抗去甲肾上腺素转运体抗体, Chemicon®, from rabbit,
物種活性
mouse, rat
應用
ELISA
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
D3900
地昔帕明 盐酸盐, ≥98% (TLC), powder,
物種
human
PHR1679
盐酸托莫西汀, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
D-906
去甲丙咪嗪盐酸盐标准液 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
1044469
（R）-托莫西汀 盐酸盐, United States Pharmacopeia (USP) Reference Standard,
物種
human
M9651
马普替林 盐酸盐, >99% (HPLC), powder,
物種
human

Small Molecule - Substrate

產品編號
描述
物種
1301801
单硫酸胍乙啶, United States Pharmacopeia (USP) Reference Standard,
物種
human
BP181
单硫酸胍乙啶, British Pharmacopoeia (BP) Reference Standard,
物種
human
1076352
Bretylium tosylate, United States Pharmacopeia (USP) Reference Standard,
物種
human